Thoroughly revised and updated, this volume is the most comprehensive, current, and practical reference on transfusion science and medicine. The book is now divided into six major sections with subsections organized around the biology and clinical use of blood components and derivatives; the transfusion needs of specific patient groups; and disease transmission and transfusion reactions. The blending of transfusion sciences with clinical concerns has been strengthened in this edition, and includes 26 case studies based on actual patients. Other Third Edition highlights include new chapters on specialized therapeutic hemapheresis procedures, transfusion-transmitted infection risk, prion transmission, and pathogen reduction.